Figure 4
From: Synthetic versus natural curcumin: bioequivalence in an in vitro oral mucositis model
Effect of nCUR versus sCUR on bacterial invasion. Determination of invasion of Detroit cells by M. catarrhalis strain 25238 using a gentamicin protection assay. Cells were pre-treated with 0, 100 or 200 μM of nCUR or sCUR, respectively, for 1 hour. Following 3 hours of infection, extracellular bacteria were killed by exposure to gentamicin for 2 hours. Following cell lysis, quantitative bacterial cultures identified viable intracellular bacteria. The ANOVA overall p value was 0.112. In-between column p values were > 0.05. Mean adherence ratios + 1 SEM of three independent experiments, each run in triplicate, are shown.