Case no. | Product | Adverse event/symptom | Outcome | ||||||
---|---|---|---|---|---|---|---|---|---|
Drug | Typea | Dosage | Adverse event | Details | Onset | Seriousness | Causality assessment | ||
1 | andrographis (325 mg/cap) | S | 5 cap PO, OD | anaphylactic shock | Angioedema, urticaria, BP 90/60 | 30 min | serious (hospitalization or prolongation of hospitalization) | Certain | Complete recovery without lesion |
2 | andrographis (352 mg/cap) | S | 3 cap 1 time used | anaphylactic shock | Urticaria, BP 87/73 | 1 day | serious (hospitalization or prolongation of hospitalization) | Probable | Complete recovery without lesion |
paracetamol (500 mg) | O | 1 tab PO, OD | |||||||
chlorpheniramine (4 mg) | O | 1 tab PO, TID | |||||||
3 | andrographis | S | 2 cap 1 time used | anaphylactic shock | Urticaria, BP 90/70 | 30 min | serious (hospitalization or prolongation of hospitalization) | Probable | Complete recovery without lesion |
paracetamol (500 mg) | O | 2 tab PO, prn | |||||||
4 | andrographis | S | 2 cap 1 time used | anaphylactic shock | Oedema, uticaria, chest pain, BP 130/70 | 1 day | serious (hospitalization or prolongation of hospitalization) | Probable | Complete recovery without lesion |
5 | andrographis (352 mg/cap) | S | 1 cap PO, TID | anaphylactic shock | Puffy eyelid, lung wheezing, drowsiness, BP 80/50 | 1 day | serious (life threatening) | Certain | Complete recovery without lesion |
6 | andrographis | S | 1750 mg 1 time used | anaphylactic reaction | Urticaria, sweat increased, nausea, BP 96/59 | 10 min | serious (hospitalization or prolongation of hospitalization) | Probable | Complete recovery without lesion |
7 | andrographis | S | 350 mg PO, 1 time used | anaphylactic reaction | anaphylactic reaction, BP 120/80 | 45 min | serious (life threatening) | Probable | Complete recovery without lesion |
8 | andrographis | S | 400 mg 2 time used | anaphylactic reaction | Oedema eyelid, wheezing, rash, BP 153/101 | 16 hr | serious (hospitalization or prolongation of hospitalization) | Probable | Complete recovery without lesion |
9 | andrographis | S | 2 cap PO, 1 time used | anaphylactic reaction | Urticaria, rash, chest tightness, , tachycardia | 5 min | serious (hospitalization or prolongation of hospitalization) | Probable | Complete recovery without lesion |
10 | andrographis | S | 4 cap PO, TID | angioedema | Angioedema, urticaria | 1 day | Non-serious | Certain | Complete recovery without lesion |
11 | andrographis | S | 3 cap PO, TID | angioedema | - | 1 day | Non-serious | Possible | Complete recovery without lesion |
guaifenesin (100 mg) | O | 1 tab PO, TID | |||||||
Salbutamol (4 mg) | O | 1 tab PO, TID | |||||||
12 | andrographis | S | N/A | angioedema | - | N/A | Non-serious | Possible | Complete recovery without lesion |
ranitidine | O | N/A | |||||||
hydrochlorothiazide | O | N/A | |||||||
Curcuma longa Linn. | O | N/A | |||||||
13 | andrographis | S | N/A | angioedema | - | 1 day | Non-serious | Probable | Still has some symptom |