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Table 4 Herbal medicines with pre-clinical evidence not included in this review

From: Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratory evidence for effects with corroborative clinical findings

Herbal medicine

Pre-clinical evidence for (potential) effects in reproductive endocrinology in PCOS and associated oligo/amenorrhoea and hyperandrogenism

Reason for exclusion

Curcuma longa (turmeric)

Anti-androgen effects [102].

No clinical evidence examining effectiveness in women was found.

Matricaria chamomilla (Chamomile)

Reduced luteinising hormone and improved ovarian morphology in animals with PCOS [103].

No clinical data found.

Mentha piperita (peppermint)

Anti-androgen effects in animals [104].

No clinical data for women.

Silybum marianum (St Marys thistle)

Anti-proliferative antioxidant and biochemical effects in the liver [105].

No clinical evidence including women was found.

  1. Studies investigating chemical compounds derived from the herbal medicines, included in this review but investigating different outcomes were found for Vitex agnus-castus [70] and Cimicifuga racemosa [106].