Antihypertensive potential of the aqueous extract which combine leaf of Persea americana Mill. (Lauraceae), stems and leaf of Cymbopogon citratus (D.C) Stapf. (Poaceae), fruits of Citrus medical L. (Rutaceae) as well as honey in ethanol and sucrose experimental model

Table 2 Effect of the extract on blood glucose and lipid profile

	Glucose (mg/dL)	Triglycerides (mg/dL)	Total cholesterol (mg/dL)	HDL–cholesterol (mg/dL)	Atherogenic index
Water	110.60 ± 10.65	152.38 ± 9.98	156.41 ± 8.61	74.49 ± 5.43	0.51 ± 0.07
Ethanol	152.50 ± 13.29^c	213.33 ± 7.33^aα	210.25 ± 15.74	45.68 ± 4.40^a	0.78 ± 0.03^b
Sucrose	165.95 ± 8.23^c	221.58 ± 4.53^aβ	222.56 ± 17.16^c	44.61 ± 4.31^a	0.80 ± 0.02^b
EtOH+ Su	153.31 ± 10.42^c	257.14 ± 2.24^a	234.35 ± 15.16^b	36.52 ± 3.18^a	0.84 ± 0.01^a
EtOH + Su + Nif	113.76 ± 13.25	51.42 ± 5.25^aα	153.84 ± 6.01 ^β	70.59 ± 4.61^α	0.54 ± 0.04^α
EtOH + Su + Ext50	126.27 ± 13.47	90.79 ± 4.77^aα	185.12 ± 14.80	47.00 ± 3.57^b	0.74 ± 0.01^b
EtOH + Su + Ext100	101.48 ± 8.53^γ	68.57 ± 4.77^aα	145.12 ± 14.47^β	55.38 ± 3.00^γ	0.61 ± 0.02^γ
EtOH + Su + Ext150	110.11 ± 9.59^γ	51.42 ± 3.38^aα	135.38 ± 9.84^α	69.04 ± 3.94^α	0.47 ± 0.08^α

Each value represents a mean ± S.E.M.; n = 5; ^ap < 0.001; ^bp < 0.01, ^cp < 0.05: significantly different compared to water. ^αp < 0.001, ^βp < 0.01, ^γp < 0.05: significantly different compared to ethanol and sucrose. EtOH + Su = Ethanol and Sucrose; Ext50, Ext100 and Ext150 = Extract at the respective doses of 50, 100 and 150 mg/kg; Nif = Nifedipine.

ISSN: 2662-7671