Effect of selected local medicinal plants on the asexual blood stage of chloroquine resistant Plasmodium falciparum

Table 5 The summary of antiplasmodial level of extracts from different parts of 14 plant species

Antiplasmodial level	Plant species	Parts	Extracts
Good EC₅₀ = 0.1-1.0 μg/ml	A. muricata	Leaves	DCM, MeOH, H₂O
	B. javanica	Green seeds	MeOH
		Roots	DCM, MeOH
		Leaves	DCM
	E. scaber	Leaves	MeOH
	M. elliptica	Leaves	H₂O
	C. iners	Leaves	H₂O, MeOH
Good to moderate EC₅₀ = 1.1- 10 μg/ml	V. amygdalina	Leaves	DCM, MeOH and H₂O
	A. galanga	Rhizomes	DCM, MeOH and H₂O
	T. catappa	Leaves	DCM, MeOH and H₂O
	C. mangga	Rhizomes	DCM, MeOH and H₂O
	C. aeruginosa	Rhizomes	DCM, MeOH and H₂O
	C. zedoaria	Rhizomes	DCM
	E. scaber	Leaves	DCM
	B. javanica	Leaves	MeOH and H₂O
		Roots	H₂O
		Green seeds	H₂O
		Black seeds	MeOH and H₂O
	C. iners	Leaves	DCM
	V. neguno	Leaves	DCM and MeOH
	M. elliptica	Leaves	DCM and MeOH
	C. phaeocaulis	Rhizomes	DCM and MeOH
Weak EC₅₀ = 11-25 μg/ml	C. phaeocaulis	Rhizomes	H₂O
	B. javanica	Green seeds	DCM
		Black seeds	DCM
	L. indica	Leaves	DCM, MeOH and H₂O
	C. zedoaria	Rhizomes	MeOH and H₂O
	V. negundo	Leaves	H₂O
	E. scaber	Leaves	H₂O
		Roots	DCM, MeOH and H₂O

The level of efficacy of extracts were ranked according EC₅₀ values which based on the threshold for in vitro antiplasmodial activity proposed by Rasoanaivo et al. [41]. Forty one extracts from 13 plant species were categorized to have good and good to moderate antiplasmodial level.

ISSN: 2662-7671