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Table 2 Effect of GS on histopathological changes of colonic tissues of rats with AA-induced UC

From: Pretreatment of Gymnema sylvestre revealed the protection against acetic acid-induced ulcerative colitis in rats

 

Ulceration

Hyperemia

Necrosis

Edema

Cellular Infiltrate

Goblet Cell Hyperplasia

Cont

0

0

0

0

0

0

AA

3

3

4

3

4

2

GS(50) + AA

2

2

2

2

2

1

GS(100) + AA

1

1

1

1

2

1

GS(200) + AA

0

1

0

1

1

0

MES + AA

0

1

0

1

1

0

  1. 0: No abnormality detected;
  2. 1: Damage or active changes < 25%;
  3. 2: Damage or active changes < 50%;
  4. 3: Damage or active changes < 75%;
  5. 4: Damage or active changes > 75%.