Figure 1From: Naja naja atra venom ameliorates pulmonary fibrosis by inhibiting inflammatory response and oxidative stress Effects of NNAV on pulmonary index and HYP content. Pulmonary fibrosis was induced with intraperitoneal injection of LPS once a week for 8 weeks or a single intratracheal administration of bleomycin. Mice and rats were administered saline or NNAV orally 4 days prior to LPS and BLM and continued until to the end of experiment. (A) Pulmonary index 6 h after LPS treatment. (B) Pulmonary index 8 weeks after LPS treatment. (C) Pulmonary index 8 weeks after BLM treatment. (D) HYP levels 8 weeks after LPS treatment. (E) HYP levels 8 weeks after LPS treatment. *P<0.05, **P<0.001, model group compared to control group; #P<0.05, ##P<0.001, NNAV-treated groups compared to model group. N =10 per group.Back to article page