Compounds | IC50(μM) | ||
---|---|---|---|
AR | AGEs | COLO 320 | |
1 | 14.83 ± 0.28△ | 57.06 ± 7.54 | >100 |
2 | 2.39 ± 0.20*** | 28.73 ± 2.96 | 24.10 ± 3.26 |
3 | 1.83 ± 0.02*** | 8.48 ± 1.43* | 22.56 ± 4.51△ |
4 | 1.22 ± 0.06*** | 5.58 ± 0.48*** | 3.53 ± 0.42** |
5 | 0.43 ± 0.06*** | 3.27 ± 0.09*** | 2.86 ± 0.39** |
6 | 0.63 ± 0.12*** | 0.75 ± 0.21*** | 2.43 ± 1.01** |
kaempferol-3-O-glc | 10.40 ± 0.18** | 42.64 ± 3.73 | 58.84 ± 3.26 |
7 | 6.33 ± 1.10** | 12.69 ± 5.17△△ | 10.07 ± 1.84* |
8 | 0.46 ± 0.01*** | 4.43 ± 0.36*** | 5.49 ± 0.23* |
9 | 1.73 ± 0.14*** | 5.21 ± 0.75*** | 3.67 ± 0.09** |
Qu | 12.35 ± 1.06 | ||
AG | 10.68 ± 1.06 | ||
5-Fu | 8.79 ± 2.57 |