Figure 3

Dose response curves of inhibitory activities of emodin, baicalin, icariin, kaempferol, celastrol and curcumin. The IC₅₀ values were calculated by fitting with the four parameter logistic (4-PL) model: A. emodin IC₅₀=81.05 μM, R²=0.97. B. baicalin IC₅₀=83.52 μM, R²=0.99. C. icariin IC₅₀=88.67 μM, R²=0.99. D. kaempferol IC₅₀=106.74 μM, R²=0.99. E. celastrol IC₅₀=114.02 μM, R²=0.98. F. curcumin IC₅₀=114.27 μM, R²=0.99. R², adjust R square values. Dose response curves of inhibitory activity were presented. Data are shown as mean ± SD of three independent experiments.