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Table 3 Effect of ETAS in hot-plate test in mice

From: Central-stimulating and analgesic activity of the ethanolic extract of Alternanthera sessilis in mice

Treatment (n=6)

Dose (mg/kg)

Reaction time (sec)

0 min

30 min

60 min

90 min

120 min

Control

-

4.23 ± 0.07

4.21 ± 0.05

4.18 ± 0.04

4.23 ± 0.05

4.17 ± 0.05

Morphine

5

4.02 ± 0.05

6.03 ± 0.05*

8.03 ± 0.07*

10.05 ± 0.09*

8.91 ± 0.09*

A. sessilis

250

4.49 ± 0.06

5.20 ± 0.05*,#

6.87 ± 0.03*,#

5.92 ± 0.07*,#

5.06 ± 0.05*,#

500

4.48 ± 0.07

5.78 ± 0.03*

7.28 ± 0.08*,#

6.14 ± 0.05*,#

5.51 ± 0.05*,#

  1. Values are mean ± SEM. *p < 0.001 vs. control, #p < 0.001 vs. morphine, the data was analyzed by two way ANOVA followed by Bonferroni’s test.