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Table 2 Cytotoxicity [Expressed as IC 50 (μg/mL)] of crude extract of Eichhornia crassipes and its fractionated products on different tumor cell lines

From: Cytotoxic and antioxidant properties of active principals isolated from water hyacinth against four cancer cells lines

Materials

IC50(μg/mL)

 

HeLa cell line

HepG2 cell line

MCF-7 cell line

EACC

Crude extract

1.6 ± 0.5j

7.6 ± 1.5i

1.2 ± 0.2i

6.04 ± 0.5j

Compound A

7.7 ± 4g

40.2 ± 10.1c

13.6 ± 5.3g

8.61 ± 2.1f

Compound B

10.7 ± 1.3d

28.3 ± 3.7d

13.4 ± 1.9g

17.3 ± 3.5b

Compound C

12.8 ± 5.1b

74.2 ± 12.5a

19.4 ± 9.2e

7.29 ± 1.6h

Compound D

4.3 ± 2.3i

23.6 ± 7f

27.2 ± 2.5d

6.42 ± 0.8i

Compound E

9.9 ± 3.4e

56.1 ± 12.3b

31.4 ± 9.6c

8.19 ± 1.2g

Compound F

6.9 ± 3.1h

14.9 ± 8.1h

41.3 ± 6.4b

9.9 ± 2.6e

Compound G

9.0 ± 3.7f

23.8 ± 5.4e

17.5 ± 4.7f

12.7 ± 4.2c

Compound H

14.1 ± 7.0a

15.4 ± 3.6g

11.1 ± 6.1h

12.3 ± 2.7d

Compound I

11.8 ± 7.0c

0.8 ± 0.4j

69.1 ± 4.9a

22.8 ± 6.9a

*DOX

0.28 ± 0.07j

0.42 ± 0.05j

0.42 ± 0.11j

--

LSD 0.01

0.225

0.16

0.284

0.188

  1. Each value is presented as mean of triple treatments, means within each row with different letters differ significantly at P < 0.01 according to Duncan’s multiple range test.
  2. *DOX: Doxorubicin (Standard anticancer drug).