Amelioration of lipopolysaccharide-induced liver injury by aqueous rooibos (Aspalathus linearis) extract via inhibition of pro-inflammatory cytokines and oxidative stress

Table 4 The effect of rooibos supplementation on in vivo total antioxidant capacity and markers of lipid peroxidation in plasma and liver of all experimental rats

Tissue	Parameter	Control	LPS	Rooibos	Rooibos + LPS
Plasma	Total polyphenol	96.69 ± 9.49	73.37 ± 6.83^*	91.94 ± 8.49	85.69 ± 12.24^#
	ORAC	1791.67 ± 167.21	1499.48 ± 375.47	1842.11 ± 345.04	1708.30 ± 528.84
	CD	85.79 ± 5.81	88.40 ± 8.56	84.34 ± 10.66	85.11 ± 8.17
	MDA	1.96 ± 0.21	2.40 ± 0.20^*	1.79 ± 0.25	1.76 ± 0.32^#
Liver	ORAC	19.06 ± 4.33	17.40 ± 4.14	21.98 ± 3.27	18.51 ± 4.50
	CD	10.38 ± 1.12	12.78 ± 0.79	11.62 ± 0.62	11.84 ± 0.47
	MDA	64.83 ± 5.46	92.65 ± 7.57^*	64.44 ± 7.57	72.27 ± 7.79^#

Values are mean ± SD (n = 9-10) *Significantly different from control (p < 0.05). ^#Significantly different from LPS (p < 0.05). CD (conjugated dienes; nmole/L in plasma, nmole/g tissue in liver), MDA (malondialdehyde; μmole/L in plasma, μmole/g tissue in liver), LPS (lipopolysaccharide), ORAC (oxygen radical absorbance capacity; μmole trolox equivalent/L in plasma, μmole trolox equivalent/g tissue in liver), Total polyphenol (μmole gallic acid equivalent/L).

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