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Table 5 Collagenase inhibition activity of CPE, AA and PBE with NNGH at 1.3 μM for positive control inhibitor

From: Phenolic composition, antioxidant, anti-wrinkles and tyrosinase inhibitory activities of cocoa pod extract

Sample Concentration (μg/ml) IC 50     
  7.8     15.6     31.3     62.5     125     250     500     1000      
NNGH, 1.3 μM 95.91 ± 0.23a -
  AA 31.87 ± 3.40 44.06 ± 0.07 48.70 ± 2.92 33.84 ± 1.00 31.70 ± 2.36 61.75 ± 8.51bcδ 52.91 ± 4.24 90.16 ± 1.27 261.38
  PBE 54.96 ± 6.77bδε€ 50.81 ± 0.90 53.32 ± 0.53 54.04 ± 1.48 16.79 ± 2.27 60.56 ± 4.98c€ 46.00 ± 1.64 39.26 ± 3.98 356.01
  CPE 53.15 ± 0.95 48.81 ± 2.55 53.23 ± 0.41 50.71 ± 0.31 38.53 ± 4.22 68.71 ± 2.12 29.97 ± 1.36 71.44 ± 2.28 111.29
  1. a b c dDifferent alphabet in column means significantly different within sample.
  2. α β γ δ ε € £different symbol means significantly different within concentration for each sample in row.