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Table 4 Gastroprotective effect of CPRHE against ethanol-induced gastric injury

From: Evaluation of acute toxicity and gastroprotective activity of curcuma purpurascens BI. rhizome against ethanol-induced gastric mucosal injury in rats

Animal Groups Animal Groups pH of Gastric tissue Mucus Weight (g) Ulcer area (mm)2 Inhibition (%) MDA (μmol/g protein) SOD (U/g protein) Nitric oxide (μmol/g protein)
A Normal control 7.02 ± .004 0.89 ± 0.03 - - 10 ± 1.1 528 ± 16.51 10 ± 1.3
B Lesion control 2.99 ± 0.17 0.41 ± 0.01 880 ± 16.23 - 28 ± 2.98 333 ± 9.98 5.9 ± 0.47
C Treatment control 6.14 ± 0.24* 0.79 ± 0.03* 195 ± 8.97* 77 13 ± 0.71* 481 ± 12.22* 9.1 ± 1.4*
D CPRHE (200 mg/kg) 4.47 ± 0.09* 0.68 ± 0.02* 455 ± 12.24* 48 21 ± 0.22* 393 ± 7.67* 7.6 ± 0.8*
E CPRHE (400 mg/kg) 5.82 ± 0.41* 0.72 ± 0.02* 325 ± 10.67* 63 17 ± 0.41* 459 ± 10.73* 8.4 ± 0.9*
  1. All values are expressed as mean ± SD. *indicates (P <0.05) compared to the (B) lesion control group. CPRHE: C. purpurascens rhizome hexane extract.