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Table 3 Serum biochemical analysis of rats. Effect of CPRHE on (a) renal function test, (b) liver function test and (c) hematology analysis of the rodents

From: Evaluation of acute toxicity and gastroprotective activity of curcuma purpurascens BI. rhizome against ethanol-induced gastric mucosal injury in rats

Animal groups Serum biochemical analysis
  (a) Kidney biochemical parameters
  Sodium (mM/L) Potassium (mM/L) Chloride (mM/L) Co2(mM/L) Anion (mM/L) Urea (mM/L) Creatinine ( μ M/L)
Vehicle 142.23 ± 0.45 4.85 ± 0.06 104.59 ± 0.45 23.89 ± 0.64 19.36 ± 0.48 5.28 ± 0.58 30.75 ± 1.87
CPRHE (1 g/kg) 143.54 ± 0.37 5.12 ± 0.72 106.24 ± 0.54 21.49 ± 0.73 19.58 ± 0.75 5.93 ± 0.43 29.81 ± 2.27
CPRHE (2 g/kg) 143.85 ± 0.82 4.91 ± 0.034 105.27 ± 0.56 22.85 ± 0.48 19.95 ± 0.39 5.68 ± 0.37 31.46 ± 2.19
Animal groups (b) Liver biochemical parameters
  Total protein (g/L) Albumin (g/L) Globulin (g/L) TB ( μ mol/L) CB ( μ mol/L) AP (IU/L) ALT (IU/L) AST (IU/L) GGT (IU/L)
Vehicle 60.76 ± 0.94 9.56 ± 0.39 51.07 ± 1.28 2.19 ± 0.13 0.87 ± 0.17 154.45 ± 5.37 50.49 ± 1.34 173.82 ± 5.38 3.45 ± 0.27
CPRHE (1 g/kg) 58.37 ± 0.57 8.35 ± 0.53 50.68 ± 1.32 2.14 ± 0.16 0.91 ± 0.14 153.23 ± 5.87 45.65 ± 1.74 175.48 ± 6.49 3.37 ± 0.53
CPRHE (2 g/kg) 59.67 ± 1.29 8.87 ± 0.19 50.25 ± 1.45 2.15 ± 0.14 0.84 ± 0.16 155.73 ± 6.82 46.76 ± 1.48 176.27 ± 6.52 3.57 ± 0.43
Animal groups (c) Hematological parameters
  HGB (g/dL) HCT (%) RBC (10 6 /μL) MCV (fL) MCH (pg) MCHC (g/dL) RDW (%) WBC (10 3 /μL) Platelet (10 3 /μL)
Vehicle 15.03 ± 0.13 46 ± 0.00 9.38 ± 0.13 59.12 ± 0.65 19.25 ± 0.31 34.22 ± 0.19 17.03 ± 0.44 6.12 ± 0.47 986.75 ± 23.65
CPRHE (1 g/kg) 15.47 ± 0.13 46 ± 0.00 9.64 ± 0.18 58.54 ± 0.63 18.89 ± 0.36 34.04 ± 0.33 18.23 ± 0.58 6.23 ± 0.34 995.36 ± 25.32
CPRHE (2 g/kg) 15.98 ± 0.12 46 ± 0.00 9.83 ± 0.16 57.78 ± 0.76 18.59 ± 0.29 33.93 ± 0.28 18.77 ± 0.34 6.31 ± 0.39 1011.52 ± 23.18
  1. Values expressed as mean ± SEM. ALT, alanine aminotransferase; AST, aspartate aminotransferase; AP, alkaline phosphatase; CB, conjugated bilirubin; GGT: G-glutamyl transferase; HCT, hematocrit; HGB, hemoglobin; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; RBC, red cell count; RDW, red cell distribution width; TB: total bilirubin; WBC, white cell.
  2. The results did not show any significant difference between groups.