Figure 1

Effect of RM on lung infection induced by the P. aeruginosa PAK strain. (A) The survival rate of mice treated with RM or Cef upon challenge with P. aeruginosa. The survival rate was assessed for 24 h; (B) lung tissue pathology slices (the light microscopic images were captured at 100× magnification); (Control) control group, (Model) model group, (Cef) positive control group, (RM-H) high dose RM group, (RM-M) middle dose RM group,(RM-L) low dose RM group. Comparing with the control group, obvious inflammatory cell infiltration in mucosa and submucosa in model group; (C) effects of RM on the production of TNF-α, IL-6, IL-8 in mouse serum.Value were expressed as the mean ± SEM (n = 6). *p < 0.05, **p < 0.01,***p< 0.001, compared to the model group (,). ^### p< 0.001 compared to the control group.