Figure 3

Anti-thrombotic effects of alpha-linolenic acid. (a) Effects of ALA on hemorrhage time; (b) Effects of ALA on coagulation time; (c) Effect of ALA on trombus formation analysis, mortality was calculated to determine the survival rate; (d) Effect of ALA on artery-venous (A-V) bypass thrombosis, the wet weight of thrombus was determined by subtracting the weight of dry cotton thread; (e) Rat platelets were isolated and platelet aggregation was determined in vitro. Aspirin (100 mg/kg), α-LNA 1–3 (pure ALA: 50, 100 and 250 mg/kg), α-LNA 4–6 (ALA mixture: 50, 100 and 250 mg/kg), * p < 0.05, ** p < 0.01 vs. control group.