In vitro anti-Onchocerca ochengi activities of extracts and chromatographic fractions of Craterispermum laurinum and Morinda lucida

Table 2 Chromatographic profile and activity of nine fractions of CL _LMeOH on microfilariae motility

Eluent	Combined Fractions: code	% inhibition of microfilarial motility on day 5 concentration of extracts (μg/ml)
Hex:EtOAc	Combined Fractions: code	500	250	125	62.5	31.25	15.63	7.8	0	IC₅₀of mfs
100:0	1-14: A	0	0	0	0	0	0	0	0	/
90:10	15-20: B	100	50	0	0	0	0	0	0	250
80:20	21-28: C	100	100	100	0	0	0	0	0	93.5
70:30	29-39: D	100	100	25	25	0	0	0	0	187.5
60:40	40-60: E	100	100	75	50	25	0	0	0	62.5
40:60	61-67: F	100	100	100	100	75	50	0	0	15.63
CH₂Cl₂:MeOH
20:80	68-78: G	100	100	100	100	100	50	0	0	15.63
95:5	79-99: H	100	75	50	25	0	0	0	0	125
0:100	100-108: I	0	0	0	0	0	0	0	0	/

Hex: hexane, EtOAc: ethyl acetate, TLC: thin layer chromatography, CH₂Cl₂: methylene chloride, MeOH: methanol.

ISSN: 2662-7671