Figure 4
From: Polysaccharopeptide enhanced the anti-cancer effect of gamma-tocotrienol through activation of AMPK
PSP and γ-T3 activates AMPK signalling pathway in vivo. Immunostaining was performed on xenograft tumor collected from the mice with the indicated treatment. Consecutive sections were stained with antibody against phospho-AMPKα (Thr172) and phospho-ACC (ser79). Note that an increase in cytoplasmic expression of both proteins was observed in tumors co-treated with γ-T3 and PSP (200× magnifications).