Figure 8From: Annona muricata leaves induced apoptosis in A549 cells through mitochondrial-mediated pathway and involvement of NF-κB Effect of AMEAE on mRNA expression of A549 cells. Downregulation of (A) Bcl-2 and upregulation of (B) Bax at gene expression level induced by AMEAE at 20 and 40 μg/mL concentrations after 24 h assessed by quantitative PCR analysis. The data represent the means ± SEM of three independent experiments. *p < 0.05 compared with the untreated group.Back to article page