Figure 3

Rikkunshito stimulates VIP promoter activity in PC12 cells. PC12 cells were treated with forskolin alone or in combination with rikkunshito (A), or rikkunshito, TPA, or IBMX (B) for 6 h. Data are presented as the mean ± SEM of quadruplicate independent experiments. *, p < 0.05 vs. 0% rikkunshito at each forskolin concentration tested, two -tailed Student’s t-test.