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Table 3 Body weight changes of Micronucleus test in mice following administration of Guibi-Tang (GBT) extract

From: Genotoxicity evaluation of Guibi-Tang extract using an in vitro bacterial reverse mutation assay, chromosome aberration assay, and in vivo micronucleus test

Group

Vehicle control

GBT

GBT

GBT

Positive control

Dose (mg/kg)

0

500

1000

2000

70

Day 1 (Mean ± S.D)

34.6 ± 0.79

34.7 ± 1.34

34.8 ± 1.14

35.1 ± 0.57

35.5 ± 0.63

Day 2 (Mean ± S.D)

34.9 ± 1.42

35.2 ± 1.21 

35.2 ± 1.19

35.3 ± 0.96

35.3 ± 0.40

Day 3 (Mean ± S.D)

34.8 ± 1.04

35.5 ± 1.11 

35.2 ± 0.72

35.0 ± 0.69

34.5 ± 0.67

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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