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Table 1 MTS cytotoxic effect of GTT and HC on human glioma cancer cells (1321N1, SW1783, LN18)

From: Gamma-tocotrienol and hydroxy-chavicol synergistically inhibits growth and induces apoptosis of human glioma cells

Cell lines

Compound

IC50 value (μg/ml)

Viability (% cells)a

Grade II

Gamma-tocotrienol (GTT)

100 ± 10.22

4.2 ± 1.34

1321N1

Hydroxy-chavicol (HC)

75 ± 7.51

5.2 ± 0.89

Grade III

Gamma-tocotrienol (GTT)

79 ± 5.29

5.5 ± 2.48

SW1783

Hydroxy-chavicol (HC)

95 ± 5.83

10.5 ± 2.04

Grade II

Gamma-tocotrienol (GTT)

42 ± 2.52

5.1 ± 1.82

LN18

Hydroxy-chavicol (HC)

119 ± 7.77

9.6 ± 1.66

  1. aPercentage of cell viability after 24 h incubation of maximum concentration treatment (200 μg/ml) of each compound.
  2. Viable cells (%) were expressed as the mean ± SD of three independent experiments.