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Table 2 Effect estimate of the number of participants with improvement of symptoms

From: Chinese herbal medicine Guizhi Fuling Formula for treatment of uterine fibroids: a systematic review of randomised clinical trials

Symptoms

Study ID

RR [95% CI]

P value

Guizhi Fuling Formula versus mifepristone

Heavy menstrual bleeding

aHu WH a [15]

1.20 [0.63, 2.29]

0.58

bHu WH b [15]

1.25 [0.67, 2.32]

0.48

Xiong DM [31]

1.09 [0.89, 1.34]

0.42

Prolonged menstrual bleeding

Hu WH a [15]

1.05 [0.77, 1.44]

0.76

Hu WH b [15]

1.03 [0.76, 1.40]

0.86

Xiong DM [31]

1.10 [0.92, 1.30]

0.30

Vaginal bleeding at times other than menstruation

Hu WH a [15]

1.20 [0.63, 2.29]

0.58

Hu WH b [15]

1.25 [0.67, 2.32]

0.48

Xiong DM [31]

2.00 [0.37, 10.92]

0.42

Distention pain of lower back and abdomen

Hu WH a [15]

1.10 [0.79, 1.55]

0.57

Hu WH b [15]

1.18 [0.88, 1.58]

0.27

Xiong DM [31]

1.20 [0.77, 1.87]

0.41

Dysmenorrhea

Hu WH a [15]

1.16 [0.77, 1.74]

0.48

 

Hu WH b [15]

1.21 [0.84, 1.75]

0.30

 

Xiong DM [31]

2.27 [1.04, 4.97]

0.04

Guizhi Fuling Formula versus other Chinese patent medicine

Prolonged menstrual bleeding

Long X [44]

0.91 [0.73, 1.13]

0.38

Heavy menstrual bleeding

Long X [44]

0.85 [0.67, 1.10]

0.22

Distention of lower abdomen

Long X [44]

0.96 [0.76, 1.21]

0.73

Guizhi Fuling Formula plus mifepristone versus mifepristone

Heavy menstrual bleeding

Chen LQ [21]

1.11 [0.94, 1.31]

0.24

Xiong DM [24]

1.13 [0.93, 1.37]

0.22

Prolonged menstrual bleeding

Chen LQ [21]

1.05 [0.89, 1.23]

0.56

Xiong DM [24]

1.10 [0.92, 1.30]

0.30

Vaginal bleeding at times other than menstruation

Chen LQ [21]

1.60 [0.55, 4.68]

0.39

Xiong DM [24]

1.13 [0.42, 3.00]

0.81

Distention pain of lower back and abdomen

Chen LQ [21]

1.60 [0.95, 2.68]

0.08

Xiong DM [24]

1.74 [0.98, 3.09]

0.06

Dysmenorrhea

Chen LQ [21]

1.31 [0.92, 1.86]

0.14

 

Xiong DM [24]

2.35 [1.15, 4.82]

0.02

  1. aHu WH a: Guizhi Fuling capsules were taken 3# three times daily for 6 months; bHu WH b: Guizhi Fuling capsules were taken 5# three times daily for 2 months and 3# three times daily for 4 months.