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Figure 4 | BMC Complementary and Alternative Medicine

Figure 4

From: Therapeutic effect and mechanism of electroacupuncture at Zusanli on plasticity of interstitial cells of Cajal: a study of rat ileum

Figure 4

Confocal images showing the ICCs in the rat colon immunolabeled for DOG1. (A-D) on frozen sections, (E-H) on whole-mount preparations, (A, E): normal small intestine, (B, F): oral to the occlusion clip, (C, G): beneath the occlusion clip, (D, H): aboral to the occlusion clip. In the normal small intestine, DOG1-like immunoreactivity (DOG1-LI) was localized in two distinct populations of ICC (ICC-MY and ICC-DMP) within the tunica muscularis and DOG1-LI ICCs were normally present with famose processes and intact cellular networks (A, E). Beneath and oral to the clip, the density of DOG1-LI ICCs were significantly reduced, the distribution was not continuous, and ICC networks were partly damaged (B, C, F, G). Aboral to the clip, ICC networks and function were essentially normal (D, H).

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