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Table 2 Effect of JSOG-6 on the serum parameters in OVX mice

From: Effects of JSOG-6 on protection against bone loss in ovariectomized mice through regulation of osteoblast differentiation and osteoclast formation

  Calcium concentration Potassium concentration ALP activity TRAP activity Osteocalcin level CTx level
Sham 9.1 ± 0.4 8.0 ± 0.3 67.6 ± 2.8 9.1 ± 0.9 148.9 ± 5.3 69.5 ± 4.3
OVX 9.3 ± 0.3 8.3 ± 0.4 85.0 ± 3.1 19.8 ± 1.0 176.9 ± 4.7 95.7 ± 3.8
E2 9.1 ± 0.6 7.9 ± 0.2 59.9 ± 3.1* 10.8 ± 1.0* 141.9 ± 4.9* 76.6 ± 4.7*
JSOG-6       
50 mg/kg 9.4 ± 0.5 7.9 ± 0.3 59.3 ± 3.8* 11.6 ± 1.4* 165.0 ± 6.6 92.3 ± 3.6
150 mg/kg 9.4 ± 0.6 7.9 ± 0.3 62.8 ± 4.6* 9.7 ± 1.1* 155.8 ± 5.1* 89.7 ± 5.2
450 mg/kg 9.6 ± 0.4 8.1 ± 0.4 65.9 ± 3.4* 8.3 ± 0.7* 153.0 ± 5.3* 83.6 ± 3.8*
  1. The serum levels of calcium, potassium, ALP, CTx, OCN, and TARP were analyzed as described in the Methods. Data represent the mean ± S.D. (n = 8). *P < 0.01 indicates statistically significant differences from the OVX mice group.