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Table 4 Effect of METS 50, 100 and 150 mg/kg in Tail immersion test

From: Antioxidant, total phenolic contents and antinociceptive potential of Teucrium stocksianum methanolic extract in different animal models

Samples

Dose mg/kg

Tail withdrawing time in sec

  

0 min

30 min

60 min

90 min

120 min

1% tween 80

10 ml/kg

3.45 ± 0.26

3.48 ± 0.19ns

3.27 ± 0.032ns

3.48 ± 0.20ns

3.57 ± 0.19

METS

50 mg/kg

3.48 ± 0.19

3.57 ± 0.19ns

4.11 ± 0.12ns

4.16 ± 0.12ns

4.09 ± 0.11ns

100 mg/kg

3.53 ± 0.18

4.25 ± 0.04ns

4.49 ± 0.13ns

4.39 ± 0.08ns

4.29 ± 0.04ns

150 mg/kg

3.57 ± 0.19

4.82 ± 0.04ns

5.48 ± 0.02ns

5.27 ± 0.05ns

5.18 ± 0.06ns

TramadolR

30 mg/kg

3.48 ± 0.20

4.99 ± 0.33

5.69 ± 0.02

5.49 ± 0.06ns

5.38 ± 0.05ns

Antinociceptive effect of METS and TramadolR antagonized by Naloxone

METS

150 mg/kg

3.52 ± 0.02 ns

2.64 ± 0.01ns

2.87 ± 0.02ns

2.73 ± 0.01ns

2.69 ± 0.01ns

TramadolR

30 mg/kg

3.50 ± 0.02

2.35 ± 0.02

2.69 ± 0.01

2.75 ± 0.02

2.65 ± 0.02

  1. nsValues statistically non significant when compared to control using one way ANOVA followed by Dunnett’s multiple comparison test.