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Table 4 Effect of METS 50, 100 and 150 mg/kg in Tail immersion test

From: Antioxidant, total phenolic contents and antinociceptive potential of Teucrium stocksianum methanolic extract in different animal models

Samples Dose mg/kg Tail withdrawing time in sec
   0 min 30 min 60 min 90 min 120 min
1% tween 80 10 ml/kg 3.45 ± 0.26 3.48 ± 0.19ns 3.27 ± 0.032ns 3.48 ± 0.20ns 3.57 ± 0.19
METS 50 mg/kg 3.48 ± 0.19 3.57 ± 0.19ns 4.11 ± 0.12ns 4.16 ± 0.12ns 4.09 ± 0.11ns
100 mg/kg 3.53 ± 0.18 4.25 ± 0.04ns 4.49 ± 0.13ns 4.39 ± 0.08ns 4.29 ± 0.04ns
150 mg/kg 3.57 ± 0.19 4.82 ± 0.04ns 5.48 ± 0.02ns 5.27 ± 0.05ns 5.18 ± 0.06ns
TramadolR 30 mg/kg 3.48 ± 0.20 4.99 ± 0.33 5.69 ± 0.02 5.49 ± 0.06ns 5.38 ± 0.05ns
Antinociceptive effect of METS and TramadolR antagonized by Naloxone
METS 150 mg/kg 3.52 ± 0.02 ns 2.64 ± 0.01ns 2.87 ± 0.02ns 2.73 ± 0.01ns 2.69 ± 0.01ns
TramadolR 30 mg/kg 3.50 ± 0.02 2.35 ± 0.02 2.69 ± 0.01 2.75 ± 0.02 2.65 ± 0.02
  1. nsValues statistically non significant when compared to control using one way ANOVA followed by Dunnett’s multiple comparison test.