Samples | Dose | Number of writhes | % inhibition |
---|
1% tween 80 | 10 ml/kg | 60.166 ± 4.167 |
-
|
METS | 50 mg/kg | 30.166 ± 4.070 | 49.862*** |
100 mg/kg | 22.833 ± 2.786 | 62.05*** |
150 mg/kg | 10.166 ± 2.786 | 83.103*** |
Acetylsalicylic acid | 100 mg/kg | 15.166 ± 3.656 | 74.793 |
- Results of multiple comparison Dunnetts test in one-way ANOVA; Groups significantly different *** p ≤ 0.001 when compared to positive control group. Percent inhibition was calculated in comparison to control group. F = 187.523, d.f. = 29. ED50 for analgesic effect of METS was 50.68 mg/kg (b.w). ***p ≤ 0.001, **p ≤ 0.01 and *p ≤ 0.05 vs. control group (n = 6).