Perilla Extract improves gastrointestinal discomfort in a randomized placebo controlled double blind human pilot study

Table 3 Mean values and standard deviation (SD) for the whole sample of Gastrointestinal symptoms and the delta changes between the run in phase and the intake phase (week 3-4)

Whole sample size (N = 47)	Placebo				Perilla				Placebo	Perilla
Whole sample size (N = 47)	Run In	Intake week 1-2	Intake week 3-4	p value (ANOVA)	Run In	Intake week 1-2	Intake week 3-4	p value (ANOVA)	Delta week 3-4 to run in	Delta week 3-4 to run in	Comparison between groups (95% CI)
Bloating	1.45	1.44	1.2	0.0733	1.42	1.28	0.98	0.0003	-0.25	-0.44	-0.194 to 0.562
SD	0.74	0.72	0.77		0.81	0.64	0.78		0.71	0.56	-0.194 to 0.562
Passage of gas	1.47	1.57	1.37	0.2284	1.6	1.5	1.3	0.0264	-0.10	-0.30	-0.177 to 0.577
SD	0.66	0.53	0.62		0.77	0.62	0.74		0.62	0.66	-0.177 to 0.577
GI rumbling	1.51	1.33	1.18	0.0635	1.64	1.27	1.09	0.0014	-0.33	-0.55	-0.251 to 0.685
SD	0.86	0.91	0.83		0.85	0.6	0.81		0.71	0.87	-0.251 to 0.685
Feeling of fullness	1.08	1.05	0.83	0.0987	1.03	0.84	0.67	0.0152	-0.24	-0.36	-0.288 to 0.515
SD	0.8	0.59	0.62		0.77	0.63	0.63		0.64	0.72	-0.288 to 0.515
Abdominal discomfort	1.15	1.06	0.84	0.0345	1.25	0.92	0.71	0.0004	-0.31	-0.54	-0.156 to 0.621
SD	0.93	0.84	0.81		0.86	0.61	0.74		0.55	0.75	-0.156 to 0.621

For the comparison within group p values of repeated measures ANOVA and for the comparison between groups the 95% confidence intervals of differences are shown.

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