A preliminary evaluation of antihyperglycemic and analgesic activity of Alternanthera sessilis aerial parts

Table 2 Analgesic effect of crude methanol extract of A. sessilis aerial parts (MEAAS) in acetic acid-induced pain model mice

Treatment	Dose (mg/kg body weight)	Mean number of abdominal constrictions	% inhibition
Control	10 ml	5.8 ± 0.37	-
Aspirin	200 mg	4.0 ± 0.84	31.0*
Aspirin	400 mg	2.8 ± 0.37	51.7*
(MEAAS)	50 mg	4.2 ± 0.49	27.6*
(MEAAS)	100 mg	3.6 ± 0.51	37.9*
(MEAAS)	200 mg	3.4 ± 0.40	41.4*
(MEAAS)	400 mg	3.2 ± 0.37	44.8*

All administrations (aspirin and extract) were made orally. Values represented as mean ± SEM, (n = 5); *P < 0.05; significant compared to control.

ISSN: 2662-7671