A preliminary evaluation of antihyperglycemic and analgesic activity of Alternanthera sessilis aerial parts

Table 1 Effect of crude methanol extract of A. sessilis aerial parts (MEAAS) on blood glucose level in hyperglycemic mice following 120 minutes of glucose loading

Treatment	Dose (mg/kg body weight)	Blood glucose level (mmol/l)	% lowering of blood glucose level
Control	10 ml	5.60 ± 0.27	-
Glibenclamide	10 mg	2.86 ± 0.26	48.9*
(MEAAS)	50 mg	4.32 ± 0.16	22.9*
(MEAAS)	100 mg	3.88 ± 0.24	30.7*
(MEAAS)	200 mg	3.06 ± 0.11	45.4*
(MEAAS)	400 mg	3.02 ± 0.17	46.1*

All administrations were made orally. Values represented as mean ± SEM, (n = 5); ^* P < 0.05; significant compared to hyperglycemic control animals.

ISSN: 2662-7671