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Table 2 Total path length travelled in the Barnes maze and total errors

From: In vitro and ex-vivo cellular antioxidant protection and cognitive enhancing effects of an extract of Polygonum minus Huds (Lineminus) demonstrated in a Barnes Maze animal model for memory and learning

 

Total path length (Mean ± SE)

Total errors (Mean ± SE)

Treatment

Day-1

Day-2

Day-3

Day-4

Day-1

Day-2

Day-3

Day-4

G. biloba 50 mg/kg

1538.99

497.76

324.95

212.4

32.35

11.9

9.46

8.00

 

±185.09

±73.89

±82.76

±25.16

±3.54

±1.69

±2.77

±1.34

P. minus 50 mg/kg

1420.44

732.61

556.98±

340.38

33.77

22.03

18.77

12.18

 

±171.2

±137.06a

117.97a

±65.71

±3.67

±4.25a

±3.83a

±2.41

P. minus 100 mg/kg

1436.37±

602.87

356.95±

244.47

31.92

15.71

10.85

7.88

 

160.44b

±96.82

51.28

±26.89

±3.06

±2.2

±1.78

±1.18

Donepezil 1 mg/kg

1031.39

559.37±

396.59±

305.24

20.79

12.95

11.36

9.00

 

±173.06b

137.29

71.57

±36.59

±3.65

±2.5

±1.6

±1.09

Veh/Sco

1841.41±

817.31 ± 1

537.84±

365.66

44.06

21.65

16.58

13.00

 

238.12a

90.27a

111.44a

±86.44

±5.22a

±3.91a

±3.27

±2.74

Veh/Veh

926.06 ± 1

234.06 ± 2

202.36±

211.82

19.09

6.75

5.98

6.40

 

96.13b

7.8b

24.26

±30.61

±3.19

±1.24

±0.87

±1.27

  1. aSignificance when compared to control vehicle + vehicle, p < 0.05.
  2. bSignificance when compared to control vehicle + scopolamine, p < 0.05.
  3. Veh = vehicle; Sco-Scopolamine; Don = Donepezil.