Decrease of a specific biomarker of collagen degradation in osteoarthritis, Coll2-1, by treatment with highly bioavailable curcumin during an exploratory clinical trial

Table 3 Summary of the visits

	Patients	Blood collection	Adverse events	Concomitant treatment	Drop off
V1	22	22	-	-	-
V2	22		9.1%	50.0%
(7 days)	22		9.1%	50.0%
V3	22	22	14.3%	45.4%	1
(14 days)	22	22	14.3%	45.4%	1
V4	21		14.3%	35.0%	1
(28 days)	21		14.3%	35.0%	1
V5 (84 days)	20	20	25%	55.6%

V1: first visit, at the time of selection; V2: visit after 7 days of treatment ; V3: visit after 14 days of treatment; V4: visit after 28 days of treatment; V5: visit after 84 days of treatment.
Knee OA patients with night pain and effusion were asked to take 2x3 caps of an enriched curcumin extract twice a day for 3 months from V1. They were visited after 7, 14, 28 and 84 days of treatment.

ISSN: 2662-7671