Skip to main content

Advertisement

Table 1 α- glucosidase and α-amylase inhibition activity of Compounds 1, 2 and 3

From: Target guided isolation, in-vitro antidiabetic, antioxidant activity and molecular docking studies of some flavonoids from Albizzia Lebbeck Benth. bark

Samples Inhibition (%)
α-Glucosidase from saccharomyces cerevisiae α-Amylase from bacillus subtilis
Compound 1 (7-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one) 93.91 ± 1.21*** 93.98 ± 1.02***
Compound 2 ((S)-2-(3,4-dihydroxyphenyl)-7,8-dihydroxychroman-4-one) 73.14 ± 1.30** 84.36 ± 0.60***
Compound 3 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one) 92.59 ± 1.36*** 90.10 ± 0.58***
Acarbose 43.77 ± 1.67 37.65 ± 0.94
  1. Statistically significant differences are designated by asterisks and double asterisks (***p < 0.001, **p < 0.01 compared to acarbose).