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Table 4 Cytotoxicity of acetone leaf extracts from nine species of the Fabaceae family on Vero monkey kidney cells and their selectivity index (SI) against bacterial strains

From: In vitro antibacterial, antioxidant and cytotoxic activity of acetone leaf extracts of nine under-investigated Fabaceae tree species leads to potentially useful extracts in animal health and productivity

Plant name

IC50(μg/ml)

Selectivity index (LC50/MIC)

  

SA

EF

EC

PA

BC

ST

Podalyria calyptrata

131.98 ± 24.87a

<0.1

0.21

0.43

<0.3

<0.1

0.82

Xylia torreana

82.51 ± 9.46b

0.27

0.52

0.27

0.27

0.52

0.52

Lonchocarpus nelsii

81.09 ± 7.18b

<0.1

1.01

0.13

<0.1

0.13

1.01

Indigofera cylindrica

77.59 ± 6.10b

0.13

0.25

0.25

0.25

0.48

1,94

Dalbergia nitidula

51.28 ± 11.47c

0.32

0.32

0.32

0.17

0.64

0.32

Crotalaria capensis

45.47 ± 10.48c

0.07

0.57

0.07

0.07

0.15

2.27

Virgilia divaricata

30.08 ± 4.96c

0.1

0.05

0.1

<0.1

0.38

0.38

Erythrina caffra

19.93 ± 2.20d

<0.1

0.25

0.12

0.12

0.06

0.06

Baphia racemosa

10.7 ± 3.47e

0.03

0.07

0.02

<0.1

0.02

0.02

Doxorubicin

2.29 ± 1.04f

nd

nd

nd

nd

nd

nd

  1. For IC50, n = 3, means values with different superscript letters are significantly different at p < 0.05; nd: not determined. In bold are interesting results with SI value >1. SA: Staphylococcus aureus, EF: Enterococcus faecalis, BC: Bacillus cereus, EC: Escherichia coli, PA: Pseudomonas aeruginosa, ST: Salmonella typhimurium.