Phenolic contents, antioxidant and anticholinesterase potentials of crude extract, subsequent fractions and crude saponins from Polygonum hydropiper L

Table 3 BChE inhibitory potential of plant extracts

Samples	Concentrations (μg/ml)	Percent inhibition (mean ± SEM)	IC₅₀(μg/ml)
Ph.Cr	1000	75.29 ± 0.64**	285
	500	64.72 ± 0.89***
	250	47.44 ± 0.86***
	125	42.78 ± 0.45***
Ph.Hex	1000	90.30 ± 1.42	40
	500	84.80 ± 0.41*
	250	69.51 ± 0.59***
	125	65.90 ± 0.32***
Ph.Chf	1000	85.94 ± 0.91*	215
	500	62.93 ± 1.73***
	250	51.82 ± 0.95***
	125	46.68 ± 0.22***
Ph.EtAc	1000	81.01 ± 0.97**	395
	500	59.05 ± 1.03***
	250	34.54 ± 0.60***
	125	29.88 ± 0.89***
Ph.Bt	1000	76.92 ± 1.15**	415
	500	58.89 ± 1.73***
	250	21.65 ± 2.41***
	125	18. 20 ± 0.47***
Ph.Aq	1000	87.62 ± 1.42	3
	500	84.79 ± 1.88
	250	80.79 ± 1.08*
	125	75.12 ± 0. 54**
Ph. Sp	1000	76.32 ± 0.87**	330
	500	74.33 ± 0.66**
	250	35.40 ± 0.82***
	125	30. 90 ± 0.45***
Galantamine	1000	96.00 ± 0.30	< 0.1
	500	92.90 ± 0.60
	250	89.45 ± 0.90
	125	86.23 ± 0.22

Result expressed as% inhibition cmean ± SEM of n = 3) and IC₅₀ values. Values significantly different as compare to positive control, *:P < 0.05, **:P < 0.01, ***:P < 0.001.

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