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Table 3 Effects of MEDL on serum liver biomarkers of CCl 4 - treated rats

From: Effect of methanol extract of Dicranopteris linearis against carbon tetrachloride- induced acute liver injury in rats

Treatment

Dose (mg/kg)

ALT (U/L)

AST (U/L)

ALP (U/L)

Vehicle

-

16.00 ± 2.867

93.18 ± 6.239

114.7 ± 7.055

Vehicle + CCl4

-

4291 ± 665.3a

3456 ± 633.2a

460.0 ± 49.62a

Silymarin + CCl4

200

249.1 ± 30.68b

288.1 ± 25.32b

190.2 ± 19.67b

MEDL + CCl4

50

3283 ± 686.5

4291 ± 592.0

350.2 ± 36.80 b

250

1886 ± 134.2b

1853 ± 86.77b

171.8 ± 13.04b

 

500

2298. ± 359.9b

1850 ± 228.5b

185.8 ± 10.23b

  1. Values are expressed as means ± S.E.M. of six replicates.
  2. aSignificant different as compared to the normal control group in the respective column, p < 0.05.
  3. bSignificant different as compared to negative control group in the respective column, p < 0.05.