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Table 2 Histopathological scoring of the liver section of CCl 4 -induced hepatic injury rats pretreated with MEDL

From: Effect of methanol extract of Dicranopteris linearis against carbon tetrachloride- induced acute liver injury in rats

Treatment

Dose (mg/kg)

Steatosis

Necrosis

Inflammation

Haemorrhage

Vehicle + Vehicle

-

-

-

-

-

Vehicle + CCl4

 

++

+++

++

+

Silymarin + CCl4

200

+

+

+

-

MEDL + CCl4

50

++

+

++

-

250

++

+

+

-

 

500

+

+

+

-

  1. The severity of various features of hepatic injury was evaluated based on those following scoring scheme: - normal, + mild effect, ++ moderate effect, +++ severe effect.