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Table 5 The percentage inhibition of α-glucosidase activity (0.5 mg/ml) and concentration leading to 50% inhibition (EC 50 ) of crude acetone extracts of ten Ficus species

From: Evaluation of the inhibition of carbohydrate hydrolysing enzymes, antioxidant activity and polyphenolic content of extracts of ten African Ficus species (Moraceae) used traditionally to treat diabetes

Species (%) α-glucosidase inhibitiona EC50 (μg/ml)
Ficus capreifolia 24.3 ± 1.7b > 1000
Ficus cordata 22.0 ± 3.6b > 1000
Ficus craterostoma 28.2 ± 7.0b > 1000
Ficus glumosa 38.7 ± 6.5b > 1000
Ficus lutea 64.3 ± 3.6c 290 ± 111b
Ficus natalensis 23.6 ± 8.1b > 1000
Ficus polita 29.2 ± 5.8b > 1000
Ficus religiosa 17.6 ± 8.0b > 1000
Ficus sycomorus 35.7 ± 5.4b 217 ± 69b
Ficus thonningii 25.3 ± 5.0b > 1000
Acarbose 84.8 ± 1.7 3.4 ± 0.5
  1. a% α-glucosidase inhibitory activity of crude acetone extracts of ten South African Ficus species (0.5 mg/ml) and control (acarbose) (0.02 mg/ml). Results expressed as % mean ± SEM (n = 9).
  2. b,c.No significant difference between extracts with same value, but significant difference p<0.05 between different values.