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Table 5 The percentage inhibition of α-glucosidase activity (0.5 mg/ml) and concentration leading to 50% inhibition (EC 50 ) of crude acetone extracts of ten Ficus species

From: Evaluation of the inhibition of carbohydrate hydrolysing enzymes, antioxidant activity and polyphenolic content of extracts of ten African Ficus species (Moraceae) used traditionally to treat diabetes

Species

(%) α-glucosidase inhibitiona

EC50 (μg/ml)

Ficus capreifolia

24.3 ± 1.7b

> 1000

Ficus cordata

22.0 ± 3.6b

> 1000

Ficus craterostoma

28.2 ± 7.0b

> 1000

Ficus glumosa

38.7 ± 6.5b

> 1000

Ficus lutea

64.3 ± 3.6c

290 ± 111b

Ficus natalensis

23.6 ± 8.1b

> 1000

Ficus polita

29.2 ± 5.8b

> 1000

Ficus religiosa

17.6 ± 8.0b

> 1000

Ficus sycomorus

35.7 ± 5.4b

217 ± 69b

Ficus thonningii

25.3 ± 5.0b

> 1000

Acarbose

84.8 ± 1.7

3.4 ± 0.5

  1. a% α-glucosidase inhibitory activity of crude acetone extracts of ten South African Ficus species (0.5 mg/ml) and control (acarbose) (0.02 mg/ml). Results expressed as % mean ± SEM (n = 9).
  2. b,c.No significant difference between extracts with same value, but significant difference p<0.05 between different values.