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Table 4 The percentage inhibition of α-amylase activity (1 mg/ml) and concentration leading to 50% inhibition (EC 50 ) of crude acetone extracts of the ten selected Ficus species

From: Evaluation of the inhibition of carbohydrate hydrolysing enzymes, antioxidant activity and polyphenolic content of extracts of ten African Ficus species (Moraceae) used traditionally to treat diabetes

Species

(%) α- amylase inhibitiona

EC50 (μg/ml)

Ficus capreifolia

43.8 ± 3.3b

>100

Ficus cordata

45.9 ± 5.2b

> 100

Ficus craterostoma

48.3 ± 1.6b

11.41 ± 4.68b

Ficus glumosa

65.1 ± 3.0c

> 100

Ficus lutea

95.4 ± 1.2d

9.42 ± 2.01b

Ficus natalensis

43.7 ± 1.8b

17.85 ± 4.42b

Ficus polita

40.2 ± 2.6b

> 100

Ficus religiosa

35.3 ± 2.8b

> 100

Ficus sycomorus

40.0 ± 2.8b

> 100

Ficus thonningii

37.6 ± 2.7b

> 100

Acarbose

96.7 ± 0.3

0.04 ± 0.03

  1. a% α-amylase inhibitory activity of crude acetone extracts of ten South African Ficus species (1 mg/ml) and control (acarbose) (0.04 mg/ml). Results expressed as% mean ± SEM (n = 9). b,c,dNo significant difference between extracts with same value, but significant difference p<0.05 between different values.