Figure 3

Immunohistochemical analysis of PCNA (LI%), cleaved caspase-3 (LI%), estrogen receptor-alpha (ER-α, LI%) and p63 (LI%) staining at beginning (referential biopsies) and at the end of the 4-week treatment period (mammary tumors) with tamoxifen and Gingko biloba extract. Data are expressed as the mean ± SEM. TAM = tamoxifen (10 mg/kg, i.p.); GbE 50-100 = Ginkgo biloba extract (50 or 100 mg/kg, i.g.). *Significant difference compared to groups G1, G2 and G3, p < 0.005).