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Table 2 Minimal inhibitory concentrations (MIC) of amoxicillin and oxacillin alone or in combination with increasing concentrations (0 to 256 μg/ml) of the cranberry PC fraction FC111 against S. aureus ATCC 29213 and MRSA COL

From: In vitro and in vivo antibacterial activities of cranberry press cake extracts alone or in combination with β-lactams against Staphylococcus aureus

S. aureus strains

Antibiotic

MIC of antibiotic in μg/mL in the presence of an increasing concentration of the cranberry fraction FC111, also in μg/mL (fold decrease in antibiotic MIC)a

  

0

32

64

128

256

ATCC 29213

amoxicillin

0.06

0.06 (1×)

0.06 (1×)

0.015 (4×)

0.015 (4×)

MRSA COL

 

512

4 (128×)

4 (128×)

1 (512×)

1 (512×)

ATCC 29213

oxacillin

0.5

0.06 (8×)

0.03 (16×)

0.03 (16×)

0.03 (16×)

MRSA COL

 

512

256 (2×)

128 (4×)

32 (16×)

16 (32×)

  1. a Combination of 128 or 256 μg/mL of FC111 with either antibiotic yielded FIC indices of ≤0.25 against all tested strains.