Anti-inflammatory, gastroprotective and anti-ulcerogenic effects of red algae Gracilaria changii (Gracilariales, Rhodophyta) extract

Table 3 The effects of MeOHGCM6 extract pre-treatment on the production of gastric NP-SH in EtOH-induced acute gastric mucosal injury

Pretreatment (n = 6)	Dose (mg/kg b.w.)	NP-SH concentration (nmol/g tissue)
Diluent	-	0.15 ± 0.04
NSPE	500.0	0.23 ± 0.03
OMP	20.0	0.33 ± 0.83*
MeOHGCM6	2.5	0.15 ± 0.57
	5.0	0.23 ± 0.28
	250.0	0.33 ± 0.69*
	500.0	0.41 ± 0.53*

Rats were fed with the different concentrations of MeOHGCM6 extract 30 minutes prior to feeding with absolute EtOH. Rats were sacrificed an hour later and the stomach was rapidly removed, the glandular stomach was collected and the production of NP-SH was determined. Results are expressed as mean ± S.D. from six animals.
* Significance difference in comparison to the group pre-treated with 10% Tween 20 (untreated control) value: p < 0.05.

ISSN: 2662-7671