Figure 15

Bax and Bcl2 staining of representative livers sampled from rats in different experimental groups. (A-I) Less apoptosis indicated by few Bax-positive hepatocytes (white arrow) and (B-I) more Bcl2-positive hepatocytes (black arrow) in liver tissues from cirrhosis rats. (A-II) High numbers of Bax-positive hepatocytes (White arrow) and (B-II) very less Bcl2-positive hepatocytes (black arrow) in the livers from hepatoprotected rats treated with Silymarin. (A-III) Moderate apoptosis as indicated by moderate Bax staining (white arrow) and (B-III) moderate Bcl2 staining (black arrow) indicating moderate apoptosis in the livers from rats treated with low dose CLRE. (A-V) High numbers of Bax-positive cells (white arrow) with severe apoptosis and (B-V) very less Bcl2-positive hepatocytes (black arrow) were observed in the liver of rats treated with high dose CLRE. (Original magnification ×40).