Variables | CHM (n = 106) | placebo (n = 54) | P Values |
---|---|---|---|
Week 1 | |||
Gastroenterologist TDS scores | 4.73 ± 2.21 | 5.65 ± 1.96 | 0.010 |
Patient TDS scores | 4.75 ± 2.24 | 5.59 ± 1.97 | 0.021 |
Gastroenterologist SDS scores | |||
Epigastric pain | 2.47 ± 1.91 | 2.61 ± 1.99 | 0.668 |
Epigastric burning | 0.74 ± 1.42 | 1.09 ± 1.86 | 0.218 |
Postprandial fullness and bloating | 3.70 ± 1.99 | 4.68 ± 2.02 | 0.004 |
Early satiety | 2.42 ± 2.16 | 3.39 ± 2.12 | 0.008 |
Patient SDS scores | |||
Epigastric pain | 2.42 ± 1.93 | 2.61 ± 1.99 | 0.568 |
Epigastric burning | 0.73 ± 1.42 | 1.11 ± 1.88 | 0.189 |
Postprandial fullness and bloating | 3.73 ± 2.03 | 4.63 ± 2.05 | 0.009 |
Early satiety | 2.39 ± 2.16 | 3.33 ± 2.06 | 0.009 |
Week 2 | |||
Gastroenterologist TDS scores | 3.44 ± 1.93 | 5.04 ± 2.11 | 0.000 |
Patient TDS scores | 3.42 ± 2.02 | 4.89 ± 2.17 | 0.000 |
Gastroenterologist SDS scores | |||
Epigastric pain | 1.74 ± 1.81 | 2.02 ± 1.80 | 0.350 |
Epigastric burning | 0.58 ± 1.33 | 0.85 ± 1.50 | 0.271 |
Postprandial fullness and bloating | 2.92 ± 1.66 | 4.24 ± 1.89 | 0.000 |
Early satiety | 1.82 ± 1.93 | 2.85 ± 2.03 | 0.003 |
Patient SDS scores | |||
Epigastric pain | 1.69 ± 1.79 | 1.96 ± 1.78 | 0.360 |
Epigastric burning | 0.59 ± 1.35 | 0.85 ± 1.50 | 0.291 |
Postprandial fullness and bloating | 2.92 ± 1.66 | 4.26 ± 1.85 | 0.000 |
Early satiety | 1.83 ± 1.94 | 2.85 ± 2.02 | 0.003 |
Week 3 | |||
Gastroenterologist TDS scores | 2.63 ± 1.95 | 4.31 ± 2.23 | 0.000 |
Patient TDS scores | 2.57 ± 1.98 | 4.28 ± 2.22 | 0.000 |
Gastroenterologist SDS scores | |||
Epigastric pain | 1.11 ± 1.65 | 1.74 ± 1.70 | 0.028 |
Epigastric burning | 0.27 ± 0.83 | 0.70 ± 1.34 | 0.034 |
Postprandial fullness and bloating | 2.15 ± 1.88 | 3.87 ± 1.96 | 0.000 |
Early satiety | 1.25 ± 1.82 | 2.59 ± 1.99 | 0.000 |
Patient SDS scores | |||
Epigastric pain | 1.11 ± 1.65 | 1.70 ± 1.71 | 0.039 |
Epigastric burning | 0.30 ± 0.87 | 0.70 ± 1.34 | 0.049 |
Postprandial fullness and bloating | 2.13 ± 1.89 | 3.83 ± 1.96 | 0.000 |
Early satiety | 1.19 ± 1.81 | 2.57 ± 1.95 | 0.000 |
Week 4 | |||
Gastroenterologist TDS scores | 2.03 ± 1.09 | 3.78 ± 2.35 | 0.000 |
Patient TDS scores | 1.92 ± 1.89 | 3.74 ± 2.35 | 0.000 |
Gastroenterologist SDS scores | |||
Epigastric pain | 0.92 ± 1.54 | 1.41 ± 1.65 | 0.061 |
Epigastric burning | 0.20 ± 0.75 | 0.56 ± 1.22 | 0.020 |
Postprandial fullness and bloating | 1.60 ± 1.87 | 3.35 ± 2.04 | 0.000 |
Early satiety | 0.83 ± 1.55 | 2.17 ± 1.98 | 0.000 |
Patient SDS scores | |||
Epigastric pain | 0.90 ± 1.53 | 1.41 ± 1.65 | 0.040 |
Epigastric burning | 0.20 ± 0.75 | 0.56 ± 1.22 | 0.020 |
Postprandial fullness and bloating | 1.61 ± 1.87 | 3.35 ± 2.03 | 0.000 |
Early satiety | 0.79 ± 1.54 | 2.15 ± 1.99 | 0.000 |
Week 8 | |||
Gastroenterologist TDS scores | 2.08 ± 1.07 | 3.57 ± 2.46 | 0.000 |
Patient TDS scores | 1.92 ± 1.84 | 3.61 ± 2.46 | 0.000 |
Gastroenterologist SDS scores | |||
Epigastric pain | 0.87 ± 1.59 | 1.52 ± 1.60 | 0.005 |
Epigastric burning | 0.20 ± 0.75 | 0.48 ± 1.18 | 0.084 |
Postprandial fullness and bloating | 1.64 ± 1.78 | 3.28 ± 2.24 | 0.000 |
Early satiety | 0.70 ± 1.47 | 1.83 ± 2.08 | 0.000 |
Patient SDS scores | |||
Epigastric pain | 0.86 ± 1.58 | 1.52 ± 1.60 | 0.004 |
Epigastric burning | 0.20 ± 0.75 | 0.48 ± 1.18 | 0.084 |
Postprandial fullness and bloating | 1.61 ± 1.80 | 3.20 ± 2.24 | 0.000 |
Early satiety | 0.73 ± 1.51 | 1.94 ± 2.04 | 0.000 |