BMC Complementary Medicine and Therapies

Table 2 Cytotoxic activities of agents

From: The investigation of a traditional Chinese medicine, Guizhi Fuling Wan (GFW) as an intravesical therapeutic agent for urothelial carcinoma of the bladder

	IC₅₀(mg/ml) ± standard deviation			Selectivity index (SI^c)
	HUC 4449	TSGH 8301	BFTC 905	TSGH 8301	BFTC 905
Guizhi^a	Inactive^b	Inactive^b	Inactive^b
GFW	7.1191±0.9628	0.8524±0.1125	0.3564±0.0438	8.35	19.98
Cisplatin	0.0232±0.0069	0.0041±0.0013	0.0440±0.0020	5.66	0.52
Epirubicin	0.0054±0.001	0.0019±0.0002	0.0021±0.0001	2.84	2.57
Mitomycin-C	0.0102±0.002	0.0040±0.0005	0.0041±0.0002	2.55	2.49

Data are expressed as the mean of n replicates (n≧6).
^a Non-anticancer agent and negative control.
^b IC₅₀ > 8 mg/ml is considered to be inactive.
^c SI value > 3 indicates high selectivity [9].

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ISSN: 2662-7671

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