Treatment | n | Body weight (g) | Biochemical parameters | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Day 1 | Day 14 | UR (mg/dL) | CR (mg/dL) | TPRO (g/dL) | ALB (g/dL) | AST (UI/L) | AP (UI/L) | CHOL (mg/dL) | TRGL (mg/dL) | ||
Tween | 6 | 35 ± 4 | 43 ± 7 | 64.5 ± 10.1 | 0.3 ± 0.1 | 7.0 ± 0.1 | 3.9 ± 0.3 | 320.4 ± 85.5 | 164.8 ± 74.2 | 158.8 ± 35.2 | 173.8 ± 42.5 |
EO 1 mg/kg | 7 | 34 ± 6 | 41 ± 10 | 64.4 ± 13.7 | 0.3 ± 0.2 | 7.9 ± 1.9 | 4.5 ± 0.9 | 334.2 ±5 2.7 | 131.4 ± 44.7 | 131.4 ± 27.2 | 143.6 ± 50.8 |
EO 5 mg/kg | 6 | 34 ± 2 | 42 ± 4 | 65.3 ± 13.7 | 0.2 ± 0.1 | 6.9 ± 0.8 | 4.2 ± 0.9 | 377.4 ± 83.6 | 161.9 ± 64.0 | 135.2 ± 15.6 | 130.8 ± 37.5 |
EO 10 mg/kg | 7 | 34 ± 4 | 40 ± 5 | 64.1 ± 11.9 | 0.2 ± 0.0 | 6.9 ± 0.6 | 3.9 ± 0.4 | 309.5 ± 45.2 | 123.3 ± 34.9 | 121.9 ± 20.4 * | 132.7 ± 33.4 |