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Table 3 Effect of treatments on peak blood glucose (PBG) and area under the curve (AUC) after sucrose loading (4 g/kg) in non-diabetic rats (NDRs) and STZ-diabetic rats (SDRs)

From: In vitro and in vivo effects of standardized extract and fractions of Phaleria macrocarpa fruits pericarp on lead carbohydrate digesting enzymes

Group

PBG (mmol/L)

% Reduction of PBG

AUC (mmol/L)

% Reduction of AUC

Non-diabetic rats

    

NC (vehicle)

7.35 ± 0.41

 

13.04 ± 0.54

 

ACAR (10 mg/kg)

5.53 ± 0.14*

24.76

10.22 ± 0.19*

21.63

ME (1 g/kg)

6.30 ± 0.10

14.29

11.46 ± 0.18

12.12

NBF (1 g/kg)

6.52 ± 0.18

11.29

11.65 ± 0.28

10.66

SFI (1 g/kg)

6.08 ± 0.14

17.28

11.01 ± 0.20*

15.57

Diabetic rats

    

DC (vehicle)

24.14 ± 1.14

 

43.71 ± 1.10

 

ACAR (10 mg/kg)

18.5 ± 0.96*

23.36

29.92 ± 0.78*

31.55

ME (1 g/kg)

21.5 ± 1.10

10.94

40.97 ± 1.66

6.27

NBF (1 g/kg)

20.53 ± 0.9

15.08

37.49 ± 1.45*

14.23

SFI (1 g/kg)

22.58 ± 1.45

6.46

38.27 ± 1.68*

12.46

  1. Values are the mean ± SEM, n = 6, *P < 0.05 vs. control. NC: Normal control, DC: Diabetic control, ACAR: Acarbose, ME: Methanol extract, NBF: n-Butanol fraction, SFI: Sub-fraction 1.