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Table 2 Effect of treatments on blood glucose (PBG) and area under the curve (AUC) after glucose loading (4 g/kg) in non-diabetic rats (NDRs) and STZ-diabetic rats (SDRs)

From: In vitro and in vivo effects of standardized extract and fractions of Phaleria macrocarpa fruits pericarp on lead carbohydrate digesting enzymes

Group

PBG (mmol/L)

% Reduction of PBG

AUC (mmol/L)

% Reduction of AUC

Non-diabetic rats

    

NC (vehicle)

8.9 ± 0.34

 

14.4 ± 0.32

 

ACAR (10 mg/kg)

6.5 ± 0.32*

26.97

11.2 ± 0.44*

22.22

ME (1 g/kg)

7.4 ± 0.31

16.85

12.4 ± 0.48*

13.89

NBF (1 g/kg)

7.15 ± 0.18

19.66

12.08 ± 0.28*

16.11

SFI (1 g/kg)

6.20 ± 0.15*

30.34

11.04 ± 0.09*

23.33

Diabetic rats

    

DC (vehicle)

21.92 ± 0.8

 

39.93 ± 1.75

 

ACAR (10 mg/kg)

17.37 ± 0.66*

20.76

27.47 ± 0.9*

31.20

ME (1 g/kg)

22.05 ± 0.53

-

40.08 ± 0.74

-

NBF (1 g/kg)

21.33 ± 1.22

2.69

37.05 ± 1.6

7.21

SFI (1 g/kg)

19.85 ± 1.42

9.44

34.58 ± 2.34

13.40

  1. Values are the mean ± SEM, n = 6, *P < 0.05 vs. control. NC: Normal control, DC: Diabetic control, ACAR: Acarbose, ME: Methanol extract, NBF: n-Butanol fraction, SFI: Sub-fraction 1.