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Table 4 Correlates of adverse events (AE) among over-the-counter Chinese medicine users (n = 789)

From: Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese

 

% reporting past-year adverse events

Unadjusted p-value

Multivariable regression of socio-demographic factors*

Full multivariable regression model**

% (95% CI)

OR (95% CI)

OR (95% CI)

Total sample of COTC users

3.2% (1.9-4.4)

  

--

Gender

 

0.146

  

 Male

2.2% (0.7-3.7)

 

1.00

--

 Female

4.0% (2.1-5.9)

 

1.40 (0.56-3.50)

 

Age

 

0.043

  

 18-44

1.9% (0.5-3.2)

 

1.00

--

 45+

4.4% (2.4-6.4)

 

1.30 (0.49-3.49)

 

Educational level

 

0.002

  

 F6 and higher

0.7% (0.0-1.6)

 

1.00

1.00

 Up to F5 (grade 11)

4.8% (2.8-6.7)

 

7.43 (1.74-31.8)2

9.64 (2.20-42.3)2

Household income

 

0.291

  

 HKD 15,000 or more

4.3% (1.2-7.5)

 

--

--

 HKD 0–14,999

2.7% (1.4-4.1)

   

Health insurance

 

0.100

  

 Insured

4.3% (2.2-6.3)

 

1.00

--

 Uninsured

2.2% (0.1-3.6)

 

1.34 (0.57-3.16)

 

Employment

 

0.008

  

 Employed or FT student

1.8% (0.1-3.0)

 

1.00

--

 All else

5.1% (2.7-7.5)

 

1.92 (0.79-4.64)

 

COTC Knowledge levels

 

0.307

  

 High knowledge score (> IQR)

6.0% (0.1-12.0)

  

--

 Score in interquartile range

2.9% (1.6-4.2)

   

 Low knowledge score (< IQR)

2.9% (0.0-6.9)

   

Perceived benefits

 

0.141

  

 High benefits score (>IQR)

2.2% (0.3-4.1)

   

 Score in interquartile range

4.2% (2.3-6.0)

   

 Low benefits score (< IQR)

0.9% (0.0-2.8)

   

Perceived barriers

 

0.472

  

 Low barriers score (< IQR)

3.2% (0.4-5.9)

  

--

 Score in interquartile range

2.8% (1.3-4.2)

   

 High barriers score (>IQR)

4.9% (1.0-8.7)

   

Perceived severity of COTC AE

 

0.260

 

--

 High severity score (>IQR)

2.7% (1.4-4.0)

   

 Score in interquartile range

4.3% (0.9-7.7)

   

 Low severity score (< IQR)

7.7% (0.0-18.7)

   

Perceived susceptibility to COTC AE

 

0.604

  

 High susceptibility Score (>IQR)

2.9% (0.4-5.4)

  

--

 Score in interquartile range

2.6% (1.1-4.2)

   

 Low susceptibility score (< IQR)

4.1% (1.3-6.9)

   

Preventive practices

 

0.008

  

 Low preventive practices Score (< IQR)

1.4% (0.0-3.3)

  

1.00

 Score in interquartile range

2.5% (1.0-3.9)

  

2.59 (0.55-12.1)

 High preventive practices score(>IQR )

6.0% (2.7-9.4)

  

6.47 (1.38-30.3)1

Exposed to any TCM warnings

 

0.650

  

 Yes,

2.9% (1.4-4.4)

  

--

 No/Can’t recall

3.5% (1.3-5.6)

   

Self-efficacy for obtaining reliable COTC info?

 

0.123

  

 Yes, have self-efficacy

2.4% (1.0-3.8)

  

1.00

 No/Not sure

4.4% ( 2.1-6.7)

  

1.42 (0.59-3.42)

Usual source of COTC info

    

 Health professionals

2.2% (0.0-5.3)

0.570§

 

--

 Internet

2.3% (0.0-6.9)

0.724§

 

--

 Package labels & inserts

3.1% (1.2-4.6)

0.387§

 

--

 Family & Friends

3.8% (1.8-5.9)

0.377§

 

--

 Retailers

5.6% (2.2-9.0)

0.037§

 

1.98 (0.78-5.09)

 Newspapers

6.7% (2.0-13.2)

0.109§

 

0.61 (0.11-3.26)

 TV

9.4% (2.0-16.7)

0.003§

 

2.93 (1.01-8.50)1

 Magazines

11.9% (1.7-22.1)

0.001§

 

3.32 (1.03-10.7)1

 Books

6.9% (0.2-13.6)

< 0.001§

 

2.74 (0.84-8.90)

  1. *Stepwise regression model using socio-demographic variables with p-value < 0.15 in the unadjusted analyses as candidate variables, non-significant covariates are shown with OR (95% CI) prior to removal from the final model.
  2. **Stepwise regression model using educational attainment in addition to attitudinal and behavioral variables with p-value < 0.15 in the unadjusted analyses as candidate variables.
  3. non-significant covariates are shown with OR (95% CI) prior to removal from the final model. Full Final model showed Hosmer-Lemeshow statistics = 0.595 and Variance Inflation Factor = 1.19.
  4. §p-values for comparison with those not reporting those behaviors.
  5. -- Variable not entered as candidate variable into multivariate model.
  6. 1p<0.05, 2p < 0.01.